Causes of anaemia in malaria

1.        Rapid destruction of infected R.B.C by the sporulation of parasite .

2.       Haemolysis of non-infected R.B.C particularly in case of P.falciparum which will liberate haemolysin . Haemoglobinuria and black water fever may be produced .

3.       Phagocytosis and intracellular destruction of both infected and non-infected R.B.C by the macrophages of the spleen .

4.       Failure of organs to re-convert liberated iron into haemoglobin .

In case of P.falciparum , selective parasitisation of reticulocytes is noticed , so there will be loss of blood from numerous punctiform haemorrhag