Main features of Malarial pathology

1. i)                    The cell of reticulo-endothelial system become densely pigmented with haemozoin pigment giving characteristic slate grey or black colour .
2. ii)                  There will be hyperplasia of reticuloendothelial cells
3. iii)                The lumen of the capillaries of the internal organs will be packed with infected R.B.C .
4. iv)                There will be congestion and dilatation of sinusoidal vessels . Perivascular haemorrhage may occur .
5. v)                  There will degenerative changes of parenchyma cells due to anoxia .
6. vi)                There will be fatty degeneration and ischemic fibrosis due to anaemia .
7.